BONE- Bio-fabrication of Orthopaedics in a New Era

Project Summary

A distinctive problem for NWE is the high occurrence of osteoporosis, leading to the highest rates of bone fractures of all EU regions. The number of hip replacements per 100k population is 214 in the NWE region versus the EU28 average of 153 (OECD 2016). The economic and societal burden of bone fractures is enormous and could be reduced by the implementation of affordable, curative healthcare solutions that ensure a faster recovery with lower health care costs. The emerging field of regenerative medicine offers potential solutions: smart implants, such as 3D scaffolds created through an innovative technology called electrospinning (ESP) hold the promise to support the regeneration of skeletal bone and replace the need for tissue donors, repeat operations or ongoing medication. However only local ESP technology R&D driven initiatives currently exist in NWE. The objective of BONE is therefore to accelerate the valorisation of cost-effective 3D smart implants fabricated by electrospinning technology (reaching TRL8) by collaboration between 4 research institutes, 4 business support organisations and 5 industry organisations. As such, BONE enables new jobs (15) to be created, two new products to be developed and tested in real life conditions (ESP technology and 3D smart implants) and intensive collaboration between Innovation leaders (Westphalia, London, Paris) strong innovators (Vlaams-Brabant, Southern-Limburg, Ireland) and moderate innovators (Nord-pas-de-Calais) in order to increase the regions’ innovation capacity in the area of regenerative medicine based on ESP technology.

Project Partners

Lead partner

Organisation Address Email Website
Maastricht Universiteit 40 Universiteitsingel
6229 ER
Name Contact Name Email Country
Fraunhofer Institut für Lasertechnik Nadine Nottrodt Germany
The Electrospinning Company Limited Rob McKean United Kingdom
Spraybase Ellen Byrne Ireland
Fianium Ltd Peter Moselund United Kingdom
Katholieke Universiteit Leuven, vertegenwoordigd door KU Leuven Research & Development Frank Luyten Belgium
Université de Lille Nicolas Blanchemain France
Medicen Paris Region Olivier Fontaine France


BONE represented at the European Society of Biomaterials Meeting in Dresden September 2019

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BONE: Biofabrication of Orthopedics in a New Era well represented at the European Society of Biomaterials Meeting in Dresden September 2019 by Project Partners from Spraybase, Fraunhofer ILT, Maastricht University & University of Lille 1 Sciences and Technology Looking forward to our next Progress Meeting in The Electrospinning Company Ltd. in October where we will join up with all partners. Pictured: Dr. Nadine Nottrodt, Ellen Byrne, Paul Wieringa, Feng Chai & Nicolas Blanchemain Read More

Great to see the collaboration of BONE INTERREG Partners to progress the BONE Project!

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Great to see the close collaboration between BONE Interreg NWE partners. The people of Spraybase visited the lab facilities of Maastricht Universiy- The Institute for Technology-Inspried Regenerative Medicine (MERLN). It was a joy to check in on the Spraybase Melt Electro Writing equipment and to form a roadmap for the next steps in BONE: Bio-fabrication of Orthopaedica in a New Era Interreg North West Europe (NWE) Project! Read More

BONE presented at Bioregate event in Nantes

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BONE partners participated to the BIOREGATE event in Nantes on December 12th-14th, a leading European Forum dedicated to the field of regenerative medicine. BIOREGATE was the occasion to network with key European stakeholders in the field and exchange on the project progress and perspectives, but also to gain a high visibility in front of an audience of 250+ participants. Actually, the BONE project was presented by Medicen Paris Region during a closed international interclustering workshop with representatives from Europe, US and Canada as well as during a plenary presentation by our partner University of Lille on a topic: « In vivo evaluation of 3D printed BCP scaffolds for maxillofacial bone reconstruction in a critical-size bone defect model of rabbit ». Read More

BONE project meeting combined with an BONE advisory board meeting and a lunch symposium during the ESB conference in Maastricht September 2018

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On September 9-10, 2018, the Interreg Bone Consortium held its fourth project meeting at the MERLN Institute, Maastricht University. We have had a successful two day meeting with fruitful discussions on the project progress. For the second day of the meeting we invited the BONE advisory board. The advisory board members discussed with the consortium the goals of the project and gave valuable hints towards the application and the approval of our planned technology and implants. We like to thank them for their support! During the 29th European Conference on Biomaterials (ESB 2018) the BONE consortium had the opportunity to present the project during a lunch symposium. Prof. Jürgen Groll, from Würzburg University gave a very interesting presentation on melt electro writing during this symposium. Read More

BONE lunch symposium during the European Conference on Biomaterials (ESB) in Maastricht

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On the 10th of September 2018 the Interreg BONE consortium will organize a BONE lunch symposium during the European Conference on Biomaterials (ESB) in Maastricht. During this symposium invited speaker Prof. Dr. Juergen Groll (Wurzburg University) will present his work on the use of Biomaterials in the melt ESP Technology. Also the BONE project subsidised by Interreg NWE will be presented. Read More

Kick-off BONE at Paris

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The official kick-off meeting of this international research project BONE, was held on Thursday July 6th in Paris, France at Medicen Paris Region. In addition, on Friday 7th of July, the first kick-off conference of BONE took place in conjunction with the Regenerative Medicine Europe matchmaking event organized by Medicen. This is an important event for BONE, as many of the stakeholders important to BONE are attending, spanning from academia, to industrial, regulatory body, and regional cluster actors. Read More

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