Codex4SMEs - Companion Diagnostics expedited for SMEs

Project Summary

The Interreg project Codex4SMEs (Companion diagnostics expedited for small and medium-sized businesses) project plans to improve healthcare by enhanced adoption of Personalized Medicine in North-West Europe. The objective is to establish a network, which supports SMEs along the value chain of Companion diagnostics (Cdx) development.

Companion diagnostics (Cdx) are an indispensable tool for optimum application of Personalized Medicine: they allow tests to determine the molecular causes of a disease before treatment has started. However, thus far the development of companion diagnostics has been highly time-consuming and costly, so at present it is only used in the context of very few treatments.

Codex4SMEs will establish a transnational network of nine partners and two sub-partners from seven countries and expedite the development of the SMEs’ products in the field of Cdx. There is a need to improve SMEs‘ innovative capabilities and raise both international competitiveness and the impact of North-West Europe SMEs in this global market as the USA are far ahead - Codex4SMEs will directly address this challenge.

 

Benefits for SMEs

  • Access to:
    • Sample access service
    • biomarker validation service
    • knowledge transfer service of biomarker/biobanking
    • ecosystems from 11 partners
    • transnational roadshow to venture and large pharma companies
    • business model and expert access service for business growth and scaling
  • Tailored support dependent from the product TRL levels of the SMEs

 

 

Project events & news

Events

Webinar: How to Commercialize your Biomarker Discovery

03-06-2020 – online

We are teaming up with the BIC Biomarker Commercialization project team! Are you working with biomarker development? Welcome to BIC's webinar on How to Commercialize your B... Read more

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News

Recording and slides of the Webinar 'Digital Health Data in Personalized Medicine'

Posted on 13-05-2020

On May 11th, 2020, the Codex4SMEs-project organized a webinar highlighting "Digital Health Data in Personalized Medicine". Please find the audio of the webinar and the slides of th... Read more

Innovation for Health – Codex4SMEs break-out session

Posted on 25-02-2020

A healthy future with good and affordable healthcare demands smart solutions. But those types of solutions don´t just appear out of thin air. To realise this, you need people with ... Read more

View more

Codex4SMEs_Flyer.pdf

Project Partners

  • University of Leicester, UK

    1 University Road
    Leicester
    LE1 7RH
    United Kingdom

    View partner details

  • BOM Holding BV, NL

    15 Goirlese Weg
    Tilburg
    5026
    Netherlands

    View partner details

  • Innovation and Management Centre Limited T/A WestBIC, IE

    Galway Technology Centre Mervue Business Park
    Galway
    H91 E2W5
    Ireland

    View partner details

  • InnovationQuarter, NL

    32 Prinses Margrietplantsoen
    Den Haag
    2595
    Netherlands

    View partner details

  • Medicen Paris Region, FR

    3-5 Impasse Reille
    Paris
    75014
    France

    View partner details

  • Integrated BioBank of Luxembourg, LU

    6 Rue Nicolas Ernest Barblé
    Luxembourg
    L-1210
    Luxembourg

    View partner details

  • Biobank Graz @ Medizinische Universität Graz, AT

    2 Auenbruggerplatz
    Graz
    A-8036
    Austria

    View partner details

  • CÚRAM Centre for Research in Medical Devices, IE

    Biomedical Sciences National University of Ireland Galway
    Galway
    H91 TK33
    Ireland

    View partner details

  • BioRegio STERN Managment GmbH, DE

    10 Friedrichstrasse
    Stuttgart
    70174
    Germany

    View partner details

Lead partner

Organisation Address Email Website
BioRegio STERN Managment GmbH, DE 10 Friedrichstrasse
Stuttgart
70174
Germany 		jehle@bioregio-stern.de www.bioregio-stern.de
Name Contact Name Email Country
University of Leicester, UK Carl M Edwards ce133@le.ac.uk United Kingdom
BOM Holding BV, NL Maria Hein rhein@bom.nl Netherlands
Innovation and Management Centre Limited T/A WestBIC, IE Eunan Cunningham ecunningham@westbic.ie Ireland
InnovationQuarter, NL Lonneke Baas Lonneke.baas@innovationquarter.nl Netherlands
Medicen Paris Region, FR Daniela Onofri donofri@medicen.org France
Integrated BioBank of Luxembourg, LU Monica Marchese Codex4SMEs@ibbl.lu Luxembourg
Biobank Graz @ Medizinische Universität Graz, AT Sarah Frajuk codex4smes@medunigraz.at Austria
CÚRAM Centre for Research in Medical Devices, IE John Cunningham jcunningham@nuigalway.ie Ireland
See all projects

Events

News

Innovation for Health – Codex4SMEs break-out session

Posted on

A healthy future with good and affordable healthcare demands smart solutions. But those types of solutions don´t just appear out of thin air. To realise this, you need people with ground breaking ideas, energy, perseverance and a relentless belief in the added value represented by collaborations. You could find these kind of people at the Innovation for health congress in Rotterdam. On February 13th in the framework of the congress, the Codex4SMEs break-out session took place. Read More

TRANSMED Academy - virtual learning environment by EATRIS

Posted on

Our associated partner EATRIS (European Infrastructure for Translational Medicine) is offering support via their new developed virtual learning platform 'TRANSMED academy': To support biomedical researchers to gain better understanding of translational research and medicines development, EATRIS has developed a learning platform, offering access to several online activities, free of charge. Online training modules are a great way to provide high quality, accessible, interactive training at all levels. Read More

Partners from across Europe to host event in Galway to support companion diagnostics SMEs

Posted on

WestBIC, CÚRAM, the Science Foundation Ireland Research Centre for Medical Devices at NUI Galway, and their European partners in Codex4SMEs Information and Networking Event are to host the Interreg North-West Europe project Codex4SMEs (Companion Diagnostics Expedited for Small and Medium-sized Enterprises) on Wednesday, 18 September, at Hotel Meyrick, Galway. Read More

Atriva Therapeutics Receives EU Award for Biomarker Validation

Posted on

Atriva Therapeutics GmbH, a biopharmaceutical company pioneering the development of host-targeting antiviral therapies, today announced that they have received the Biomarker Validation Award as part of the European Interreg Project Codex4SME. A total of four award winners will receive a grant of approximately 100,000 Euros each, in the form of laboratory services by the Integrated Biobank of Luxembourg. Read More

Exclusive access to biobank service

Posted on

Four companies from Germany, France and the Netherlands have been presented with the Biomarker Validation Award as part of Codex4SMEs. The European project aims to establish a transnational network to accelerate the development of companion diagnostics along the entire value chain of small and medium-sized enterprises. The award is endowed with approximately EUR 100,000, which is handed over in the form of laboratory services. The chosen companies can now have their respective biomarkers validated by the Integrated Biobank of Luxembourg – in other words, have them tested to assess their reliability with regard to their relevant indication. Read More

Presentation of the webinar with Tom Miller

Posted on

Finding capital to fund your (companion) diagnostics SME: The Venture Capital perspective. On 28 May, a webinar with Tom Miller in the frame of the Interreg NWE project 'Codex4SMEs' took place. Tom Miller is founder of Greybird Ventures and is dedicated to invest in companies that can help to eliminate "trial and error" medicine with high-specifity diagnostics and generate value for patients, providers, developers of therapies, and those who pay for healthcare. Read More

The Codex4SMEs project offers a tailored support scheme programme.

Services provided by the biobank project partners will be covered 100 % of the costs by the project.

 

Following services are still available within the project:

  • Sample Access Service provided by the Biobank Graz
  • Knowledge Transfer Services (in biomarker & biobanking topics) provided by the Biobank Graz

 

Sample Access and Knowledge Transfer services will be available continously.

Please note: there is a limited number of services available and will be revised following a 'fist come first serve basis'.

For interested SMEs the guidelines and the application documents are available for download below.

Do not hesitate to get in contact with your local Codex4SMEs-partner and/or the Biobank of Graz directly (codex4smes@medunigraz.at).

 

Biobank Graz Sample Access: Guidelines
Biobank Graz Sample Access: Application form
Biobank Graz Knowledge Transfer: Guidelines
Biobank Graz Knowledge Transfer: Application form
Biobank Graz Material Transfer Agreement

 

 

Earlier in the project, the Integrated Biobank of Luxembourg (IBBL) offered a Biomarker validation serivce for the Codex4SMEs-community. Four SMEs were awarded with the service during two call periods:

  • First call period: Oktober 15th, 2018 till December 14th, 2018
  • Second call period: February 18th, 2019 until April 19th, 2019

 

For evaluation of the application forms and professional recommendations to the Codex4SMEs-consortium, an independent expert group was integrated.

The members were:

  • Marie Souleau, European Patent Attorney
  • Patrice Debre, Pitié- Salpêtrière Hospital, INSERM

The Codex4SMEs-consortium would like to thank the expert group for their support, their time for revising the applications and helping us selecting the winners!

Find out more about the award and the winners:

Exclusive access to biobank service

The Advisory Board acts as an observing body. They provide insights and recommendations on different topics in the framework of Cdx to support the project.

These are the members:

  • Andreas Baur, BioLAGO e.V.
  • Dr. Michael Steinwand, BioLAGO e.V.
  • Sylvain Lehmann, French society of Clinical Biology
  • Philippe Manivet, French society of Clinical Biology
  • Prof. Dr. Kurt Zatloukal, Medical University of Graz
  • Prof. Dr. Berthold Huppertz, Medical University of Graz
  • Florence Bietrix, EATRIS- ERIC
  • Eric Steinfelder, BBMRI- ERIC
  • Diarmuid Cahalan, Metabolomic Diagnostics
  • Dave Mead, PhD, Medilink East Midlands
  • Ida Haisma, Leiden Bio Science Park
  • Eefje Dekkers, InnovationQuarter

The map gives an overview of companies which are active in the field of companion diagnostics in the partner regions. When you klick at one selected company, further information like the main activities or the contact datails are mentioned.

Be part of the Codex4SMEs network, contact your regional partner and get an entry on the map.

 

Benefit from the Codex4SMEs projekt and get tailored support depending on your product TRL level. Furthermore you get access to:

  • Sample access service
  • biomarker validation service
  • knowledge transfer service of biomarker/biobanking
  • ecosystems from 11 partners
  • transnational roadshow to venture and large pharma companies
  • business model and expert access service for business growth and scaling

Please find an overview of health-related Horizon 2020 - calls for your project idea.

 

Topic Budget/projet Budget/call  Type of action Deadline
SC1-BHC-37-2020: Towards the new generation of clinical trials – trials methodology
research		 4-6M 6M RIA 04.06.2020
SC1-BHC-06-2020: Digital diagnostics – developing tools for supporting clinical
decisions by integrating various diagnostic data		 8-15 M 40M RIA 04.06.2020
SC1-BHC-11-2020: Advancing the safety assessment of chemicals without the use of animal testing 10-20 M 60M RIA 04.06.2020
SC1-BHC-17-2020: Global Alliance for Chronic Diseases (GACD) - Prevention and/or
early diagnosis of cancer*		 1-3M 20M RIA 04.06.2020
SC1-BHC-20A-2020: Pre-commercial procurement (PCP) for integrated care solutions 5-6M 25M PCP (public sector)  04.06.2020
SC1-BHC-20B-2020: Public procurement of innovative solutions (PPI) for diagnostics
for infectious diseases		 3-5M 25M PCP (public sector)  04.06.2020
SC1-BHC-33-2020: Addressing low vaccine uptake 2-3M  9M RIA 04.06.2020
SC1-BHC-34-2020: New approaches for clinical management and prevention of
resistant bacterial infections in high prevalence settings		 10-15M 25M RIA 04.06.2020
SC1-BHC-35-2020: Creation of a European wide sustainable network for harmonised
large-scale clinical research studies for infectious diseases		 25-30M 30M RIA 04.06.2020
SC1-BHC-36-2020: Micro- and nano-plastics in our environment: Understanding
exposures and impacts on human health		 4-6M 25M RIA 04.06.2020
SC1-DTH-02-2020: Personalised early risk prediction, prevention and intervention
based on Artificial Intelligence and Big Data technologies		 4 - 6M 32M RIA 18.06.2020
SC1-DTH-04-2020: International cooperation in smart living environments for ageing
people		 2-4M  8M RIA 18.06.2020
SC1-DTH-06-2020: Accelerating the uptake of computer simulations for testing
medicines and medical devices		 6-8M 32M RIA 18.06.2020
ICT-46-2020: Robotics in Application Areas and Coordination & Support 6-7M 41,5M RIA 22.04.2020
ICT-47-2020: Research and Innovation boosting promising robotics applications 2-3M  20M RIA 22.04.2020
ICT-36-2020: Disruptive photonics technologies 3-6M 47,5M RIA 22.04.2020
ICT-40-2020: Cloud Computing: towards a smart cloud computing continuum 3-5M 19M RIA 22.04.2020
DT-ICT-12-2020: AI for the smart hospital of the future 7-10M 40 DONT 15M SANTE IA 22.04.2020
CE-BIOTEC-08-2020: New biotechnologies to remediate harmful contaminants 4-5M 10 RIA 20.04.2020

 

The Codex4SMEs-partners have good contacts to other biobanks.

 

Please feel free to contact us, the Codex4SMEs-partners are happy to help you in facilitating your individual biobank service, such as follows:

  • Need for a higher amount of samples (>20 samples)
  • Need for specific sample requests not available via Biobank Graz and the related free sample access service
  • Need for additional support in clinical trial/study planning (not covered within free sample access service)

Please note: costs for samples and/or other activities from other than the Biobank of Graz cannot be covered by the project.

 

BBMRI-ERIC

Biobanking and Biomolecular Resources Research Infrastructure – European Research Infrastructure Consortium, the pan-European infrastructure of national biobank networks (Homepage).

  • European research infrastructure for biobanking
  • Bringing together all the main players from the biobanking field – researchers, biobankers, industry, and patients to boost medical research.
  • Quality management services
  • Support with ethical, legal and societal issues
  • IT services:
    • Directory
      • Intended for all different types of users, providing aggregate information about biobanks and their sample/data collections.
    • Negotiator
      • Facilitating communication between researchers searching for samples/data and biobanks allowing refinmenet of their queries and once the search is done, to request samples
    • Locator
      • A tool for researchers looking for samples/data, enabling them to query available samples/data sets on the level of individual samples and/or data items, under development.
      • NOT a search tool for individual samples.
Finnish Biobank Cooperative (FINBB)

FINBB, as a member of BBMRI-ERIC, is a one-accessshop for effortless access to Finnish biobank materials and biodata:

Fingenious is a

  • Digital gateway to Finnish biobanks and biomedical research
  • Built to serve academic and industry researchers and to advance medical research globally
  • Provides a view of and access to biospecimens and data from all public biobanks in Finland, through a single point of contact

Feasibility and access costs (FINBB)

  • Initial feasibility service is free of charge.
  • Providing cost-estimation for the feasibility report if compiling the feasibility report requires exceptional effort and a significant amount of time
  • Submitting access requests through Fingenious is also free of charge. Questioner will receive a cost estimation of your biobank project during the feasibility and access request

Please find their homepage here.

Commercial Biobanks

In.vent Diagnostica GmbH

In.vent Diagnostica GmbH

  • Partner of all diagnostic Stakeholders for the procurement of biologic material of human origin (e.g., innovations, research, development, clinical studies, production, controls, standardisation, ...)
  • Active in the field of diagnostics
  • Targeted procurement of human biomaterials:
    • Standards & controls – high volumes possible
    • Quality control panels
    • Clinically defined samples
      • Highly specific parameters possible
      • Samples suitable for Clinical Performance Studies
      • Extensive global network of physicians and hospitals
  • Company owned study centre:
    • on demand blood donations
    • control over all steps of pre-analytics
  • Clinical services: Planning, Ethics, Samples, Performance Studies, Statistics, Reports (PER), Submission at NB

Reliable sources of information on the SARS-CoV-19:

International sources:

 

Mapping, data source:

 

Regulatory Issues on Covid-19

 

 

 

 

Open Access scientific sources:

 

Europe: COVID-19 exchange platforms

 

Resources for reporters:

 

 

The Market Analysis Service offered in the Codex4SMEs-project is based on information derived from widely accepted professional sources.

Here are two examples on information that an SME developing diagnostics will receive:

  • Example 1: A diagnostics company would like to know the trial status of pharmaceuticals for blood cancer treatment in order to identify and develop a biomarker for companion diagnostics in parallel.
    • The company will receive a comprehensive report of current trial status including pharmaceuticals from different types of organisations (private, public), market size, pipeline products, competitors and a forecast of the next five years.

 

  • Example 2: A company would like to receive information on Companion Diagnostic Tests in Oncology including a Global Analysis and Market Forecasts. 
    • The Market Analysis Service offered in the Codex4SMEs project will provide a comprehensive report on Market Volume, number of Companion Diagnostic Tests performed, Market Revenue, number of Pipeline Products and relevant Companies, and Competitive Assessment.

 

Please feel welcome to contact us personally if you are interested in our new market analysis service.

Your contact person is Marieke Huis in 't Veld: mhuisintveld@bom.nl

Don't be late: We are able to offer this service until July 1st 2020 !

Please find a recording of the introdcutory webinar here.

 

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