On June 3, 2022 Medicen Paris Region organized REGMED Europe, the second edition of the European event on biomaterials and regenerative medicine. Within the Cité Universitaire de Paris campus, more than 80 people from 12 European countries met to share and discuss the future of this discipline.
REGMED Europe was the opportunity to review the results of the Interreg NWE BONE project: Bio-fabrication of Orthopedics in a New Era coordinated by the University of Maastricht. This projectis coming to an end after 5 years of collaboration. The project consortium was created in 2017 following the undeniable observation that the way to curative and affordable solutions goes through 3D implants which also respond to the economic and societal repercussions of bone fractures. Together, 4 research institutes, 4 business support structures and 5 industrial players have joined forces to address the need to accelerate the development of the profitability of 3D implants produced by the MEW: Melt ElectroWriting technique.
The progress after 5 years of collaboration
The latest advances from the BONE project: Improved printing performance thanks to the development of an auger allowing the molten polymer to be extruded with more control (compared to the more common air pressure); First report of a laser irradiation system for a MEW application; Optimization of scaffolds, including the incorporation of calcium phosphate and BMP2 growth factors to improve bone regeneration; Realization of biohybrid tissue layers combining unique scaffold designs via MEW with aggregated micro-tissues from stem cells.
Advances in this area undeniably raise the question of the challenges of European regulations which were then addressed by our guest Aymeric Lebon, from Strategiqual, through the regulation of devices (Medical Device Regulatory). This promising start for the day was followed by a round table on the future of biomaterials with the shared views of Dr David Koper from Maastricht University, Dr Guillaume-A Odri from Inserm, Dr Didier Letourneur from CNRS – National Center for Scientific Research and Julien Payen, CEO and co-founder of Lattice Medical. Read More
Next week the exciting World Termis conference will take place. The BONE consortium would like to invite all of you to also visit a symposium that we are organizing within TERMIS as a satellite lunch symposium.
This symposium is on the “BONE: Bio-fabrication of orthopaedics in a new era” project, a North-West Europe Interreg consortium.
If you are attending TERMIS, please join us at this symposium too and enjoy the presentations that BONE partners have prepared.
Below see more information on the program, including the presenters and the topics.
Name of symposium: A future outlook on melt electrowriting: from academic to manufacturer to clinic
Embedded within the 6th world TERMIS congress
(15th-19th November 2021)
Time: 15th November 2021, at 12.00-13.30
Dr. Paul Wieringa (MERLN institute, Maastricht University):
Title: The BONE Project: Clinical Considerations for MEW Applications
Dr. Matei Cirstea (The Electrospinning Company):
Title: Beyond the simple scaffold: The next level of medical electrospinning
Prof. Dr. Peter Kessler (MUMC+)
Title: Bone has to be replaced by bone - a gold standard still valid today
Distinguished Prof. Dr. Dietmar Hutmacher
Title: Are MEW scaffolds having a role in bone tissue engineering? Read More
Good to see progress from the BONE consortium meeting despite the constraints of operating in the time of COVID-19.
Interreg North West Europe (NWE) BONE: Bio-fabrication of Orthopaedics in a New Era #Biomaterials #MEW #RegnerativeMedicine #TissueEngineering #SmartScaffolds #BONE #BoneRegeneration #MeltElectrowriting Read More
During the 10 and the 11th of March 2020 the BONE consortium met each other at the facilities of KUL.
As this took place just before the lock down in Belgium and the Netherlands due to COVID19, some other partners needed to join the meeting via conference call. Nevertheless flexibility was requested, the consortium succeeded to have an in-depth analysis on each work package and created a strict time line plan for the upcoming months of the project. Read More
On October 1-2, 2019, the Interreg Bone Consortium held its project meeting at the facilities of The Electrospinning Company. We have had a successful two day meeting with fruitful discussions on the project progress. For the second day of the meeting we invited the BONE advisory board. The advisory board members discussed with the consortium the goals of the project and gave valuable hints towards the application and the approval of our planned technology and implants. Read More
The BONE consortium organized a group meeting at the facilities of Université de Lille.
Besides the discussions of the different work packages the different partners had the opportunity to visit the animal facilitites of Université de Lille where part of the animal studies for the BONE project are performed as well. Read More
BONE partners participated to the BIOREGATE event in Nantes on December 12th-14th, a leading European Forum dedicated to the field of regenerative medicine.
BIOREGATE was the occasion to network with key European stakeholders in the field and exchange on the project progress and perspectives, but also to gain a high visibility in front of an audience of 250+ participants. Actually, the BONE project was presented by Medicen Paris Region during a closed international interclustering workshop with representatives from Europe, US and Canada as well as during a plenary presentation by our partner University of Lille: In vivo evaluation of 3D printed BCP scaffolds for maxillofacial bone reconstruction in a critical-size bone defect model of rabbits. Read More
On September 9-10, 2018, the Interreg Bone Consortium held its fourth project meeting at the MERLN Institute, Maastricht University. We have had a successful two day meeting with fruitful discussions on the project progress. For the second day of the meeting we invited the BONE advisory board. The advisory board members discussed with the consortium the goals of the project and gave valuable hints towards the application and the approval of our planned technology and implants. We would to thank them for their support! Read More
