NWE-Chance - Development and validation of promising integrated eHealth applications combined with nanotechnology for hospitalisation of heart failure patients at home

Project Summary

Heart failure is a growing epidemic: in the European Union about 15 million people are now living with heart failure. Between 1-2% of total healthcare expenditure can be associated with this condition, of which 50% is due to hospitalisation. Digital health is widely recognised as one of the most promising solutions to this societal challenge: in the field of cardio vascular diseases, current eHealth tools are primarily focused on rehabilitation and monitoring after hospitalisation. Today, there is a transition taking place from dedicated hospital care to the home setting, with a combination of eHealth applications and miniaturised diagnostic and therapeutic devices. This is where the NWE-Chance project comes into play.


NWE-Chance is all about bringing stakeholders together to co-create the knowledge needed to get innovation in home care to happen in North-west Europe. The project will contribute to develop SMEs’ capabilities and to increase their involvement in cooperative projects in the NWE Interreg region. During the project, two SMEs and one larger company will collaborate with three hospitals and two universities to develop and test a prototype of a platform for home hospitalisation in which supportive (miniaturised) diagnostic and therapeutic devices are integrated. The prototype will integrate a real-time monitoring system with a nano-based test for measuring potassium and creatine, and a wearable patch to monitor vital functions.

Pilots will run in three different hospitals to test:

  • the technical feasibility of the developed technologies;
  • the organisational feasibility of home hospitalisation for heart failure patients.

Then, an Innovation-Hub will be launched to:

  • support the collaboration and knowledge exchange between SMEs and hospitals in the process of developing and implementing new digital health technologies;
  • ensure continuity and growth of the collaboration between industry and hospitals, leading to the development of eHealth products to support hospitalisation at home.

Additionally, the project will deliver an Implementation Roadmap to multiply the innovations in other regions and initiate similar projects.


The industry developing innovations and transferring hospital care in a home environment is still in its infancy, fragmentally available and only partially integrated in standard healthcare services. Despite new opportunities for home hospitalisation, there are several challenges. One is the limited uptake by healthcare professionals. It is therefore crucial to:

  • establish clinical evidence that supports the use of new technologies in healthcare;
  • raise awareness about real-life examples of uptake.

Another challenge is the very few connections between the health sector and small and medium-sized enterprises (SMEs) developing eHealth tools for dedicated hospital care in the home setting. It is therefore essential to:

  • combine the separate knowledge between large-scale industry, SMEs, healthcare organisations, and knowledge providers;
  • bring together all the relevant stakeholders to exchange knowledge and experience.

The project will facilitate the process of co-creation through living labs and will launch a knowledge, testing and implementation platform that will support SMEs in their innovations in the field of digital health.


By the end of the project:

  • three industry partners will have developed new eHealth-based technologies for the transition of 24/7 hospital care for heart failure patients in the home environment;
  • the concept of home hospitalisation for heart failure patients will be adopted by three hospitals in the NWE region;
  • an Innovation Hub will be established. Innovative SMEs in the NWE region will be able to rely on an infrastructure to develop novel products.

Long-term effects in five years:

  • three industry partners have further developed new eHealth-based technologies for the transition of 24/7 hospital care for heart failure patients in the home environment;
  • the networking initiated by the Innovation Hub will have increased the adoption of home hospitalisation. Fifteen SMEs will have realised digital innovations.

Long-term effects in ten years:

  • three industry partners will have solid market positions;
  • home hospitalisation will be fully adopted;
  • the Innovation Hub will have supported the collaboration between fifty SMEs and hospitals. Thirty-five SMEs will have realised digital innovations.

Project Partners

Lead partner

Organisation Contact name Address Email Website
Isala Astrid van der Velde 2 Dokter van Heesweg
8025 AB
a.vdvelde@isala.nl www.isala.nl
Name Contact Name Email Country
Jessa Ziekenhuis Paul Dendale paul.dendale@jessazh.be Belgium
CE-Mate B.V. Steven Staal steven.staal@medimate.com Netherlands
European Health Telematics Association Elena Alberti elena.alberti@ehtel.eu Belgium
Universiteit Hasselt Valerie Storms valerie.storms@uhasselt.be Belgium
University of Strathclyde Kara Mackenzie Kara.mackenzie@dhi-scotland.com United Kingdom
Sensium Healthcare Alison Burdett alison.burdett@sensium.co.uk United Kingdom
Klinikum der Stadt Ludwigshafen am Rhein Uwe Zeymer zeymeru@klilu.de Germany
Build in Europe s.a. Marc Lange marc.lange@build-in-europe.be Belgium
HC@Home B.V. Wilma Koch wilma.koch@hcathome.com Netherlands

Press release from Isala Heart Centre

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